Spinal prilocaine. A reply

Comparative spinal neurotoxicity of prilocaine and lidocaine.

BACKGROUND Reports of major and minor sequelae following lidocaine spinal anesthesia have generated interest in an alternative short-acting intrathecal agent. Of the available anesthetics suitable for short-duration spinal anesthesia, prilocaine is perhaps the most promising agent. However, data comparing the neurotoxicity of these agents are lacking. Accordingly, the present experiments invest...

Spinal Anaesthesia for Endoscopic Urological Surgery: A Comparison of 2% Hyperbaric Prilocaine with 0,5% Hyperbaric Bupivacaine

Background and aims: Hyperbaric prilocaine is a short-acting local anaesthetic. The aim of this study is to compare the characteristics of subarachnoid block using hyperbaric prilocaine with that of bupivacaine in outpatients undergoing transurethral resection of bladder (T.U.R.B.). Methods: In this prospective randomized controlled trial, 60 patients undergoing endoscopic urological surgery re...

Prilocaine-induced Methemoglobinemia.

Dosage finding for low-dose spinal anaesthesia using hyperbaric prilocaine in patients undergoing perianal outpatient surgery.

BACKGROUND Hyperbaric prilocaine 20 mg/ml may be preferable for perianal outpatient surgery. The aim of this prospective, single-centre, randomised, single-blinded, controlled clinical trial was to determine the optimal dosage of hyperbaric prilocaine 20 mg/ml for a spinal anaesthesia (SPA) in patients undergoing perianal outpatient surgery. METHODS One hundred and twenty patients (18-80 year...

Urinary retention after spinal anaesthesia with hyperbaric prilocaine 2% in an ambulatory setting.

BACKGROUND Hyperbaric prilocaine 2% is a medium long-acting spinal anaesthetic. There are few data on time to recovery and rate of urinary retention after spinal administration of hyperbaric prilocaine 2%. This prospective study was carried out to evaluate the time to spontaneous micturition, quantify the rate of necessary bladder catheterizations, and identify the risk factors for urinary rete...